Regenerative Endodontics as the Future Treatment of Immature Permanent Teeth

The regenerative endodontic procedure (REP) is an alternative solution for treatment of permanent teeth with incomplete root apex development. It results in angiogenesis, reinnervation, and further formation. Indications REP include immature necrotic pulp inflammatory lesions the periapical tissues. main contraindications comprise significant destruction tooth tissues a lack patient cooperation. We distinguish following stages this procedure: disinfection canal, delivery components, closure cavity, follow-up appointments. For effective canal disinfection, use both rinsing agents intracanal medicaments suggested. Sodium hypochlorite triple antibiotic paste are used most commonly. Light-activated proposed as method. prerequisite regeneration process supply its essential components: stem cells, growth factors, scaffolds to lumen. Blood clotting, platelet-rich plasma, fibrin purpose. proper course REP, it also necessary close tightly. purpose, mineral trioxide aggregate (MTA), tricalcium silicate (Biodentine), or types glass ionomer cement employed. should attend regularly scheduled appointments each time undergo thorough interview, physical radiological examination. important indicator successful continued length thickness visible on X-rays. Many different proposals management protocol have been published; paper proposes authors’ original scheme. Regenerative endodontics future teeth; however, still requires lot research refine standardize protocol. application tissue engineering methods seems be promising, mature treatment.